Many lethal genetic disorders such as CF, Huntington’s, sickle cell anemia, Tay Sach’s, etc., persist in the human genome. How have these genes survived so many millennia of evolution (why didn’t they die out)?​

Answers

Answer 1

They've been under the purview of balancing selection. This type of selection occurs when two alleles – one being the harmful variant and the other being the beneficial variant – both confer some sort of benefit in the presence of each other. This can work in two ways. Sometimes the balance of deadly and beneficial alleles can create a balance in the population, allowing for genes to persist over time. In other cases, the lethal genes can be beneficial if there is an environmental change and the deadly gene can offer protection from the new environment. Both of these scenarios create a balance of selection, allowing for the persistence of the gene over time. In some cases, the lethal genes are essential for the maintenance of certain gene complexes and, if lost, could result in decreased fitness. This type of selection is known as evolutionary pressure and it can also contribute to the longevity of certain genes. A third possibility is that some of the genes simply survive due to random genetic drift.


Related Questions

What is the probability that two parents with the genotype AaBb will produce an offspring with the genotype AaBb?

Answers

The probability of parents with the AaBb genotype producing offspring with the genotype AaBb is 4/16. Thus the correct answer is (b) 4/16.

The Punnett square method is used to forecast the prospective offspring from a certain cross based on the gametes of the parents. The parents carefully create the gametes that are arranged in a checkerboard pattern so they can understand all the potential children that can be generated. The likelihood of each prospective offspring can be determined using the checkerboard method. In the cross, there are four gametes produced by each of the two dihybrid parents. As a result, the hybrid has the capacity to produce a total of 16 offspring. Out of the 16 possible combinations, only four types of offspring can have the AaBb genotype.

Parents: AaBb*AaBb

Genotypes: AB   Ab    aB   ab *  AB    Ab   aB   ab

Offspring:   ABAB    ABAb   ABaB   ABab   AbAB   AbAb  AbaB  Abab  aBAB   aBAb   aBaB   aBab   abAB  abAb  abaB  abab

Percentage: AaBb: 4/16

The complete question is:

What is the probability of an AaBb offspring when you cross AaBb x AaBb parents?

a. 1/2

b. 4/16

c. 1/8

d. 1/32

e. 1/4

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What happens in insertion mutation?

Answers

An insertion mutation changes the DNA sequence by adding one or more nucleotides to the gene.

An insertion is a point mutation in which one or more base pairs is added to a DNA sequence. Point mutations is further divided into silent mutations, missense mutations, and frameshift mutations.

Frameshift mutation is considered as a genetic mutation caused by a deletion or insertion in a DNA sequence. This kind of mutation shifts the way the sequence is read. diseases like cystic fibrosis is a result of frameshift mutation that alters the CFTR gene. The harshness of frameshift mutation is reliant on the number of nucleotides and the position of insertion of nucleotides.

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How does hypertension cause stroke?

Answers

In hypertension, The arteries that carry oxygen and blood to the brain can burst or become blocked by high blood pressure, resulting in a stroke.

There are many ways that high blood pressure can harm your health. It has the potential to seriously harm vital organs like your eyes, brain, kidneys, and heart. Your arteries may become less elastic as a result of high blood pressure, reducing the flow of blood and oxygen to your heart and resulting in heart disease. A stroke can result in severe impairments of speech, movement, and other fundamental activities. You can also die from a stroke.

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The definition of biological evolution encompasses

Answers

Answer:

Biological evolution, simply put, is descent with modification. This definition encompasses small-scale evolution (changes in gene frequency in a population from one generation to the next) and large-scale evolution (the descent of different species from a common ancestor over many generations).

Explanation:

Why are vestigial structures not removed by natural selection?

Answers

Structures that have no apparent function and appear to be residual parts from a past ancestor are called vestigial structures. Examples of vestigial structures include the human appendix, the pelvic bone of a snake, and the wings of flightless birds.

A DNA s
equence has mutated from

AAG G
CA TTC
-
t
o the sequence of

AAG GCT ATT C
-
. This mutation is an
example of a/an ___________________?
a.
Frameshift mutation
b.
Point
mutation
c.
Triple shift mutation
d.
Chromosomal
mutation

Answers

Answer:

Explanation:

The mutation is from AAG GCA TTC to AAG GCT ATTC

So there is a frameshift with an insertion of a T

Answer is a Frameshift mutation.

Answer:

Explanation:

its an example of single insertion leading to a frameshift mutation

Which hypothetical scenario would result in
the moon not having different phases?

Answer:The answer is the moon or it around earth takes while as long but I don’t know why tho, can someone explain please

Answers

Answer:

the different phases of the moon are proof that it revolves around the earth at the rate it does, so if it revolved around earth much more slowly, then the phases wouldn't be visible because the sun wouldn't hit the moon as it does now

Explanation:

i don't know why this is being taught who cares about the moon

How do glands of the endocrine system help your body maintain homeostasis?

Answers

The glands of the endocrine system secrete hormones into the bloodstream to maintain homeostasis and regulate metabolism. The hypothalamus and the pituitary gland are the command and control centers, directing hormones to other glands and throughout the body.

What is the great red spot on Jupiter
A. Hurricane
B. Thunderstorm
C. Bad Weather
D.Tornado

Answers

b.thunderstorm it has really bad winds and rain
a thunderstorm is the answer

What color light does a leaf reflect?

Answers

The specific colors of light that a leaf reflects depend on the pigments present in the leaf. Chlorophyll, which is the pigment primarily responsible for the green color of leaves.

leaf reflects green light and absorbs other colors of the visible spectrum such as blue and red. Carotenoids, which are pigments that give leaves their yellow and orange colors, leaf reflects yellow and orange light. And finally, anthocyanins which are pigments that give leaves their red, purple and blue colors, leaf reflects red, purple and blue light. Additionally to these pigments, other substances on the leaf surface can also affect the light leaf reflects. It's worth noting that while leaves reflect visible light, they also reflect other types of light such as near-infrared and ultraviolet, but these are not visible to the human eye.

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Choose all the answers that apply. Biomass includes _____. plants animals animal waste sunlight paper trash

Answers

Biomass includes plants, animals, animal waste, paper products, and trash. It can be used to generate electricity, heat, biogas, and biodiesel.

Plants are a significant source of biomass. Growing crops such as corn, wheat, and soybeans can be used to create energy in the form of ethanol, biogas, and biodiesel. The plant matter can also be burned to produce heat or electricity.

Animals are also a source of biomass. Animal manure can be used to generate biogas, which can be used to run engines or generate electricity. Animal fats and oils can also be used as biodiesel, or converted into biogas.

Animal waste is another form of biomass. Manure, animal carcasses, and other organic materials can be broken down and used to generate biogas. Animal waste can also be composted to create compost or fertilizer.

Sunlight is not a form of biomass, as it does not contain any organic material. However, it can be used to power solar cells and photovoltaic panels, which can be used to generate electricity.

Paper products, such as newspaper and cardboard, can be recycled and used to create biomass energy. This is done by breaking down paper into small, fine particles and then burning it to create heat or electricity. The paper can also be converted into biogas.

Finally, trash is a form of biomass. Food waste and other organic materials can be broken down and used to generate biogas, which can be used to run engines or generate electricity. Trash can also be burned to create heat or electricity.

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Complete question:

1.plants

2.animals

3.animal waste

4.sunlight

5.paper

6.trash

What does the grey layer(clay) do in
the soil profile?

Answers

In deeper horizons such as the B-horizon, a brown colour usually means that the soil has good natural drainage. A black or dark grey colour usually comes from an accumulation of organic matter. In areas of high rainfall, this may again mean poor drainage.

how dors raising the temperature affect the rate of nuclear decay

HELP ASAP DYE TMRRW

Answers

Unlike chemical reaction rates, which vary with the conditions of a reaction, nuclear decay rates are constant..Raising the temperature has no effect on the rate of nuclear decay.

How does temperature impact the rate of decay?

Decomposing organisms are less active in cooler temperatures, keeping the pace of decomposition low.

How is nuclear decay influenced by temperature?

A speed of alpha, beta, & electron decays all rely on temperature & whether they are contained inside an insulating or conducting material, as demonstrated by numerous groups.

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Biologists look at how organisms are related and when they first appeared on Earth. Which of the following is true about the organisms that live on Earth today?

A. All organisms that have ever lived on Earth can still be found alive today.

B. Some of the organisms alive today have been around for 4.6 billion years.

C. The organisms alive today are the same as the ones found in fossils.

D. The organisms alive today evolved from organisms that previously lived on Earth.

Answers

Answer:

the organisms alive today evolved from organisms that previously lived on Earth.

Explanation:

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The organisms that live on Earth today evolved from organisms that previously lived on Earth.

What is pre existing organism?

The focus of biogenesis states that all living organisms arise from a pre-existing living organism. The theory of biogenesis is given by Louis Pasteur.

The theory said that life comes from pre-existing life, by means of reproduction. Living beings do not arise from non-living things.

Thus, option "D" is correct,  organisms arise from a pre-existing living organism.

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Han’s younger sister is riding her tricycle in a straight line. Her speed is 2.5 m/s. After 5 seconds, she comes to a stop. What is her acceleration during this time? (Hint: when she comes to a stop her speed will be 0 m/s).

Answers

-0.5m/s^2

Explanation:

the answer is negative this only show direction that is acceleration is a vector quantity

23. Disposable nonwoven drapes: a. Are impervious to fluid strikethrough b. May be a combination of fluid-resistant and absorbent layers c. Can be reprocessed

Answers

The correct option is B ; May be a combination of fluid-resistant and absorbent layers There are two kinds of surgical drapes: reusable and disposable.

Reusable drapes are comprised of a woven cloth that is washed and sterilized between treatments.  Disposable drapes, on the other hand, are often constructed of non-woven material and are cremated after each operation.

McKesson Field Drape/Towel Non-Fenestrated is sterile and poly-lined, making it suitable for use in operating rooms. This critical medical supply item is used during surgical operations to drape over the body in order to separate the operating field. To prevent bacterial strike-through, the inner poly layer repels moisture.

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The occurrence of transitional fossils supports the idea that (select all that apply)Group of answer choices extinct and living forms are related.these are ancestors of living species.change occurs in species over time.

Answers

The occurrence of transitional fossils supports the idea that - extinct and living forms are related, these are ancestors of living species, change occurs in species over time.

A transitional fossil is that  fossilized remains of a life form which exhibits traits common to both an ancestral group and its derived descendant group which is living at present. The descendant group is sharply differentiated by gross anatomy and mode of living from the ancestral group.

These fossils show that taxonomic divisions are human made that have been superimposed on the continuum of variation. Because of the incompleteness and unavailability of the fossil record, there is usually no way to know exactly how close a transitional fossil is to the point of divergence if evolution of that particular species. Therefore, it cannot be assumed that transitional fossils are direct ancestors of more recent groups, though they are frequently used as models for such ancestors.

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Why isn't glycolysis considered a closed pathway?

Answers

Glycolysis is not considered a closed pathway because it consumes energy in the form of adenosine triphosphate (ATP) and generates energy in the form of adenosine diphosphate (ADP) and a high-energy phosphate group. Additionally, the intermediates of glycolysis, such as glucose and pyruvate, can be used in other metabolic pathways.

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Which is the most accurate evidence of an evolutionary relationship between two organisms?

A). Similarity in niche

B). Similarity in habitat

C). Similarity in behavior

D). Similarity in DNA

Answers

Answer: D

Explanation: Every other  choice can be changed with environment and other factors but DNA can effectively compare organisms.

D similarity in DNA means at one point they could have been the same

What is a possible effect of leakage of inner ear fluid?

Answers

Answer: Body imbalance such as affect balance and hearing.

Explanation:

What would happen to the population of snakes and rabbits if hawks were removed from the ecosystem?

Answers

There would be a HUGE increase to their species, because their predator would be gone. And the snakes and rabbits pray would have a huge decrease because there would be more snakes and rabbits that would eat them.

What implications could this have for this species of slug from an evolutionary standpoint? What potential advantages or disadvantages might this mutation have?

Answers

Positive mutations are essential for evolution to occur. They raise a living thing's chances of surviving or procreating. Deadly mutations can give rise to cancer or genetic diseases.

Are mutations typically detrimental?

While most mutations are beneficial, some can also be dangerous. A dangerous mutation might cause a genetic illness or a cancerous condition. Chromosome-level mutations are still another type. Chromosomes, which are little, threadlike organelles present in the cell nucleus, carry genes.

Why do mutations cause issues?

A variation can make a protein malfunction or not be created at all by altering the gene's instructions for producing it. A variation can impair normal development or result in a disease when it changes a protein that is essential to the organism.

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can some one help me ill give more points if its right. ill give like 50

Answers

Answer:Pollution enters the Earth's atmosphere in many different ways. Most air pollution is created by people, taking the form of emissions from factories, cars, planes, or aerosol cans. ... Some types of air pollution, such as smoke from wildfires or ash from volcanoes, occur naturally. These are called natural sources.

Explanation: Make sure you subscribe to my channell if you like imvu its meiyanna calloway

Answer:

Acid rain is caused by a chemical reaction that begins when compounds like sulfur dioxide and nitrogen oxides are released into the air. These substances can rise very high into the atmosphere, where they mix and react with water, oxygen, and other chemicals to form more acidic pollutants, known as acid rain.

Explanation:

Acid rain that seeps into the ground can dissolve nutrients, such as magnesium and calcium, that trees need to be healthy. Acid rain also causes aluminum to be released into the soil, which makes it difficult for trees to take up water.

What needs to be in an introductory paragraph in an interpretive essay about plays?
A.
background information on the play
B.
critical interpretations of the play
C.
a list of all the plays written by the author
D.
a definition of "plays"

Answers

Answer:

B

Explanation:

need to know this to explain what you know on the central idea of the story.

PBS Evolution: Great Transformations

1. If the world’s history were compressed into one hour, how long have humans been here?

Microbes. Single-celled organisms


2. How long ago did mammals first appear on earth?

Mammals first appeared about 200 million years ago

3. What type of animal did the skull that Dr. Gingrich discovered resemble?

Dr. Gingrich discovered resembled a whale

4. What did "Whale Valley" used to be?

Whale valley is a


5. What unusual feature did they find at the end of the early tetrapods’ limbs?


6. How long ago did animals first appear on Earth?


7. When the mouse "eyeless" gene was implanted into the fruit flies, what happened?


8. How would walking on two legs be an advantage?


9. What modifications does the human skeleton have?

Humans has the same transformation as other animals even though humans are special.


10. Summary/reflection:

Answers

Given that whales and other mammals resembled other mammals in terms of their skulls and other sculptures, based on the fossil evidence, humans have undergone evolutionary transitions.

The transition from land animals to whales is one of the most well-known instances of a supposed change cited by the evolution contingency in the opening of the program. The fossils of Pakicetus, Ambulocetus, Rhodocetus, Dorontid, and Basilosaurus show that this transition can be explained. Pakicetus only has a small portion of its cranium to display, as opposed to a whole transitional fossil.

The program portrays Ambulocetus as a fully preserved fossil of an aquatic mammal with legs, yet this is a stretch of the fact because the animal's skeleton was actually discovered to be extremely fragmented. Rhodocetus is solely represented in the series by a skull.

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periodic table of elements an atom contains 11 protons and 12 neutrons, its atomic number will be_ and the mass number will be _.

a 1, 23
b 11, 23
c 12, 11
d 23, 11

Answers

Answer: the atomic number is eleven because the number of protons is equal to the number of electrons which is also equal to the atomic number.

The atomic mass is the protons+neutrons which after adding will give 23.

Explanation:

Look at this picture. Is this bird about to become this predator’s lunch? What do you think is happening in this photo?

Answers

Answer:

I don't think it is becoming the predator lunch. there are some birds who will clean the teeth

the bird is cleaning it’s teeth. It’s called mutualism

Plant seedlings were treated with a range of concentrations of coumarin, a small organic compound. After one week, seedling height was taken as a measure of plant growth. In a separate experiment, stem tissue sections were taken from newly germinated seedlings and incubated in solutions containing 14C-glucose and coumarin. After 24 hours, the quantity of radioactive label in cytoplasmic and cell wall fractions was measured. All data are shown in the table above. Which statement is supported by these results

Answers

Coumarin is found to restrict the production of a specific component found in the cell walls but not in the cytoplasm, which plays an important role in the growth of the stem. (BIOSYNTHESIS< CYTO< STEM GROWTH)

The results from the experiment suggest that coumarin treatment negatively impacts the growth of plant seedlings, as measured by seedling height. This indicates that coumarin has an inhibitory effect on stem growth.

Additionally, the experiment that measured the number of radioactive labels in cytoplasmic and cell wall fractions revealed that coumarin affects the biosynthesis of a specific component in the cell walls but not in the cytoplasm. This suggests that coumarin specifically targets the production of a component that is critical for stem growth, and that this component is found primarily in the cell walls and not in the cytoplasm.

This is further supported by the fact that the radioactive label is found in the cell wall but not in the cytoplasm, indicating that the biosynthesis of this component is taking place in the cell wall and not in the cytoplasm. Overall, these results suggest that coumarin is inhibiting the biosynthesis of a component that is critical for stem growth, specifically in the cell walls.

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A sea otter is considered very important in
maintaining his ecosystem and food web.
Changes with him will affect the ecosystem
dramatically. A species such as this is called
a(n).
A. keystone species
B. VIP
C. ecosystem king

Answers

The answer would be Key stone species

What is the advantage of cells being so small?

A. Small cells contain a greater quantity of enzymes than large cells.

B. Small cells do not require energy and get everything they need from osmosis.

C. The cell has a smaller surface area to volume ratio which means it can move nutrients into
the cell and waste out more efficiently.

D. The cell then has a larger surface area to volume ratio which means it can move nutrients
into the cell and waste out more efficiently.

Answers

Answer:

D. The cell then has a larger surface area to volume ratio which means it can move nutrients into the cell and waste out more efficiently.

Explanation:

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